The immune response of allophenic mice to the synthetic polymer L-glutamic acid, L-lysine, L-phenylalanine. II. Lack of gene complementation in two nonresponder strains
نویسندگان
چکیده
منابع مشابه
The immune response of allophenic mice to the synthetic polymer L-glutamic acid, L-lysine, L-phenylalanine. II. Lack of gene complementation in two nonresponder strains
The genetic control of the immune response of inbred strains of mice to certain antigens has been demonstrated to be governed by a set of Ir genes linked to the major histocompatibility complex (H-2) of mice (1,2). Until recently, the control was thought to be governed by single, dominant genes, located within the I region of the H-2 complex. Merryman et al. (3) originally demonstrated that the...
متن کاملImmunosuppressive factors from lymphoid cells of nonresponder mice primed with L-glutamic acid60-L-alanine30-L-tyrosine10. IV. Lack of strain restrictions among allogeneic, nonresponder donors and recipients
The synthetic terpolymer of L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) fails to stimulate development of GAT-specific antibody responses in nonresponder mice but stimulates development of GAT-specific suppressor T cells that inhibit the development of normal anti-GAT plaque-forming cell responses to GAT complexed to methylated bovine serum albumin (MBSA). Extracts from lymphoid cells of G...
متن کاملa synchronic and diachronic approach to the change route of address terms in the two recent centuries of persian language
terms of address as an important linguistics items provide valuable information about the interlocutors, their relationship and their circumstances. this study was done to investigate the change route of persian address terms in the two recent centuries including three historical periods of qajar, pahlavi and after the islamic revolution. data were extracted from a corpus consisting 24 novels w...
15 صفحه اولThe growth response of mammalian cells in tissue culture to L-glutamine and L-glutamic acid.
Twelve n-amino acids (arginine, cystine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, tyrosine, and valine) have been found essential for the growth of two mammalian cell lines in tissue culture, a mouse fibroblast’ (strain L) (1) and a human uterine carcinoma cell (strain HeLa) (2). The minimal vitamin requirement of these cell lines has also been d...
متن کاملI. Dominant Genetic Control of Immune Responsiveness to Coi~olymers of L-glutamic Acid and L-alanine and L-glutamic Acid and L-tyrosine
The demonstration of direct genetic control of specific immune responses followed the introduction of synthetic polypeptides as experimental antigens (14) . The use of synthetic antigens, whose complexity can be controlled by varying the number and relative proportions of their constituent amino acids (5), has in fact led to several demonstrations of unigenic control of specific immune responsi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1977
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.145.3.766